This top 15 pharmaceutical/biopharmaceutical makes drugs for the brain, heart, and other body parts. The biopharmaceutical's lineup includes a blockbuster solution for rheumatoid arthritis treatment and stroke prevention. Promising growth is also represented in its antipsychotic medication and HIV treatments. Most of its sales come from products in the therapeutic areas of cardiovascular care, hepatitis, immunology, metabolics, neuroscience, oncology, and virology. Global research facilities and manufacturing plants are mainly in the US and Europe, and its products are marketed to health care practitioners, hospitals, and managed care providers in 100 countries.